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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11021 | DHODH-IN-12 | Dehydrogenase | |
DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07. | |||
T78932 | HDHODH-IN-12 | DNA/RNA Synthesis | |
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM. As the rate-limiting enzyme in the de novo synthesis of pyrimidines, critical for DNA... |